PES One by Genzeon Platforms
Genzeon · Operations & Productivity
Certification per Microsoft Marketplace.
Evidence tier Source Confirmed · 7 captures on record
What the publisher says
As described on Microsoft Marketplace.
PES One is the patient and member engagement platform from Genzeon Platforms, built on Microsoft Healthcare Agent Services and Azure AI, and powered by Aether One — Genzeon's patent-protected agentic substrate for regulated healthcare. Live with 10+ health systems in production today, PES One delivers intelligent, omnichannel engagement across voice, chat, SMS, and email with the privacy, compliance, and audit-grade traceability healthcare requires.
Designed for modern health systems and payers, PES One empowers patients and members with 24/7 self-service while reducing administrative overhead for providers. Conversational AI, Natural Language Understanding (NLU), and Microsoft Azure App Services come together to deliver experiences that resolve member problems.
Show the rest of the publisher’s description (26 more lines)
PES One is part of the Healthcare Brain, alongside HIP One (the Reasoning Lobe clinical decisioning, live in the CMS WISeR Innovation Model) and CPS One (the Prefrontal Cortex — privacy and AI governance automation, with 76 NPS and 96% three-year retention across 40+ enterprise clients). Three platforms, one architecture, 11 patents filed.
Key Capabilities
- AI-Powered Virtual Agents (IVA): Automate patient and member interactions using Azure OpenAI and Microsoft Healthcare Agent Services
- Omnichannel Communication: Unified experience across voice, SMS, chat, and email with conversation history persisting across channels
- Appointment Management: Real-time scheduling, reminders, and rescheduling integrated with Epic and other EHRs
- Prescription Refill Automation: Secure, self-service Rx management with EMR integration
- Patient Support & FAQs: 24/7 multilingual support for portal access, telehealth preparation, and common member inquiries
- Member Intelligence: Predictive routing and intent recognition on the Aether One agentic substrate (on the Healthcare Brain roadmap)
- Analytics & Insights: Actionable data on patient adherence, operational efficiency, and engagement healthOutcomes Delivered
- 64% peak containment (43% average) - Conversations resolved end-to-end without human escalation
- 47% cost savings per support call - Verified across production deployments
- 62% of account access inquiries resolved without human intervention
- 10+ health systems in production today
- CMS-grade compliance - HIPAA, SOC 2 Type II, ISO 27001Why Choose PES One
- Production-grade, not pilot-grade. Live with 10+ health systems today. The Engagement Lobe is part of the Healthcare Brain architecture that also operates the CMS WISeR Innovation Model in New Jersey for 1M+ Medicare FFS members.
- Patent-protected substrate. PES One runs on Aether One, Genzeon's agentic AI substrate for regulated healthcare - 11 patents filed. Architectural depth, not a wrapper.
- Healthcare-optimized AI. Built on Microsoft Healthcare Agent Services and Azure OpenAI, with healthcare-specific NLU and conversational patterns tuned for clinical and operational vocabulary.
- Governance built in. PES One operates alongside CPS One, the Prefrontal Cortex of the Healthcare Brain - privacy and AI governance automation engineered by privacy professionals to oversee AI workloads. Zero ONC fines across the Genzeon Platforms enterprise client base.
- EHR Integration Ready: Seamless integration with Epic, Cerner, MEDITECH, and other major EHR systems
- Azure Marketplace Hosted: Scalable, secure, and compliant - with the full Microsoft Azure infrastructure underneath
- Forward-deployed engineering: Genzeon Platforms doesn't ship and disappear. Embedded engineers, named clinical and operational reviewers, and outcome-committed engagementsTarget Customers
- Health Systems - Hospitals and integrated delivery networks looking to automate patient engagement at scale
- Hospitals - Acute care and specialty hospitals seeking to reduce call-center burden while improving patient satisfaction
- Outpatient Clinics - Practices managing appointment volume, prescription refills, and member access at scale
- Telehealth Providers - Digital health platforms requiring HIPAA-compliant conversational AI infrastructure
- Health Plans and Payers - Member services operations seeking AI-powered containment and resolution
Preview
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Compliance
- FedRAMPConfirmedNot listed90%, registry-checkedNo FedRAMP Marketplace entry matched this vendor's domain, checked 2026-08-27registry recordas observed 2026-08-27
Confirmed means matched to a public authoritative registry. Claimed means the vendor or its listing states it, not yet cross-checked. A framework not shown was not found in any source we hold, which is not evidence against it. Not listed means a scoped registry check found no match for this vendor's domain: a No is a scoped registry check, not a compliance judgment. Confidence bands: 95% domain-verified, 90% registry-checked, 80% self-attested, 70% weak signal. Self-attested items marked “vendor's site” are gathered from the vendor's own website and are not verified by us.
Vendor
External enrichment · as of 2026-08-29
Plans and pricing as listed
1 listedSources
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